Problem Statement Explorer

36 Statements. 7 Tracks.

Search by keyword or statement code, filter by track, and apply straight into the registration form with your statement preselected.

36 / 36 showing
Required for ApplyPDF Format

One-Pager Template

Official one-page idea proposal format required for all applicant teams.

Format & Sample GuideDownload Template
Official Booklet4 Pages PDF

Problem Statements (PDF)

Complete directory with all 36 challenges across all 7 biotechnology tracks.

All Tracks BB-PB to BB-OBDownload Statements

Showing 36 statements

BB-PB-01
Precision Biotherapeutics & Drug Discovery

Precision Biotherapeutics & Drug Discovery

Low-cost screening pipeline for repurposed small molecules

Design a screening and prioritisation workflow that lets a small lab shortlist existing approved molecules for a new indication using open datasets and inexpensive assays.

Apply for this statement
BB-PB-02
Precision Biotherapeutics & Drug Discovery

Precision Biotherapeutics & Drug Discovery

Targeted delivery for oncology payloads

Propose a carrier or conjugation strategy that improves tumour-site delivery while lowering systemic exposure, with a feasible path to bench validation.

Apply for this statement
BB-PB-03
Precision Biotherapeutics & Drug Discovery

Precision Biotherapeutics & Drug Discovery

Affordable biologics manufacturing at small scale

Rework an expression, purification or formulation step so a therapeutic protein can be produced reliably at pilot scale in an Indian academic or startup facility.

Apply for this statement
BB-PB-04
Precision Biotherapeutics & Drug Discovery

Precision Biotherapeutics & Drug Discovery

Antimicrobial resistance countermeasures

Develop a therapeutic or adjuvant approach against a priority resistant pathogen, including a clear resistance-development and stewardship argument.

Apply for this statement
BB-PB-05
Precision Biotherapeutics & Drug Discovery

Precision Biotherapeutics & Drug Discovery

Precision dosing for underserved patient groups

Build a method to personalise dosage for paediatric, geriatric or comorbid patients using accessible biomarkers and simple decision support.

Apply for this statement
BB-DM-01
Diagnostics & Medical Devices

Diagnostics & Medical Devices

Rapid point-of-care test for a high-burden infection

Create a sample-to-result test usable at a primary health centre with no cold chain, reporting a result in under 30 minutes.

Apply for this statement
BB-DM-02
Diagnostics & Medical Devices

Diagnostics & Medical Devices

Non-invasive screening for metabolic disease

Design a low-cost, non-invasive screening approach for diabetes or related metabolic conditions suitable for community camps.

Apply for this statement
BB-DM-03
Diagnostics & Medical Devices

Diagnostics & Medical Devices

Frugal biomedical device for rural clinics

Engineer a durable, field-repairable device that replaces an expensive imported instrument in a rural clinical workflow.

Apply for this statement
BB-DM-04
Diagnostics & Medical Devices

Diagnostics & Medical Devices

Wearable monitoring with clinically useful alerts

Turn continuous sensor data into a small number of trustworthy clinical alerts, addressing false positives and patient adherence.

Apply for this statement
BB-DM-05
Diagnostics & Medical Devices

Diagnostics & Medical Devices

Maternal and newborn health diagnostics

Propose a diagnostic or triage tool that catches a common maternal or neonatal risk earlier in low-resource settings.

Apply for this statement
BB-BG-01
Bioinformatics, Genomics & Bio-AI

Bioinformatics, Genomics & Bio-AI

Variant interpretation for Indian population genomes

Build an interpretation or annotation workflow that accounts for under-represented Indian population variation in clinical reporting.

Apply for this statement
BB-BG-02
Bioinformatics, Genomics & Bio-AI

Bioinformatics, Genomics & Bio-AI

Protein structure and function prediction for orphan targets

Use structure prediction and docking to characterise a poorly annotated target and propose testable hypotheses.

Apply for this statement
BB-BG-03
Bioinformatics, Genomics & Bio-AI

Bioinformatics, Genomics & Bio-AI

Open pathogen genomic surveillance dashboard

Design a pipeline and dashboard that turns sequencing submissions into timely, shareable outbreak intelligence.

Apply for this statement
BB-BG-04
Bioinformatics, Genomics & Bio-AI

Bioinformatics, Genomics & Bio-AI

Multi-omics integration for disease subtyping

Combine two or more omics layers to separate clinically meaningful disease subtypes, with honest validation on held-out data.

Apply for this statement
BB-BG-05
Bioinformatics, Genomics & Bio-AI

Bioinformatics, Genomics & Bio-AI

Bio-AI assistant for wet-lab protocols

Build a model-assisted tool that helps researchers plan, troubleshoot and record experiments without hallucinating protocol steps.

Apply for this statement
BB-AG-01
Climate-Resilient Agriculture & Agri-Biotech

Climate-Resilient Agriculture & Agri-Biotech

Drought and salinity tolerance in staple crops

Identify traits, markers or bio-inputs that keep yields stable under water stress or rising soil salinity.

Apply for this statement
BB-AG-02
Climate-Resilient Agriculture & Agri-Biotech

Climate-Resilient Agriculture & Agri-Biotech

Early crop disease detection in the field

Combine biology and imaging or sensing so a farmer can detect an outbreak days earlier than visual inspection allows.

Apply for this statement
BB-AG-03
Climate-Resilient Agriculture & Agri-Biotech

Climate-Resilient Agriculture & Agri-Biotech

Biofertilisers and microbial consortia for degraded soils

Formulate a microbial product with a realistic shelf life and application method for smallholder plots.

Apply for this statement
BB-AG-04
Climate-Resilient Agriculture & Agri-Biotech

Climate-Resilient Agriculture & Agri-Biotech

Post-harvest loss reduction with bio-based solutions

Reduce spoilage in a specific crop supply chain using coatings, controlled ripening or biological preservatives.

Apply for this statement
BB-AG-05
Climate-Resilient Agriculture & Agri-Biotech

Climate-Resilient Agriculture & Agri-Biotech

Livestock and aquaculture health management

Improve disease prevention, feed efficiency or antibiotic reduction in an Indian livestock or aquaculture system.

Apply for this statement
BB-FN-01
Functional Foods, Nutrition & Smart Proteins

Functional Foods, Nutrition & Smart Proteins

Affordable alternative protein from local feedstock

Develop a protein ingredient from a regionally abundant crop, by-product or microbial source with credible cost and taste targets.

Apply for this statement
BB-FN-02
Functional Foods, Nutrition & Smart Proteins

Functional Foods, Nutrition & Smart Proteins

Micronutrient fortification that survives Indian cooking

Deliver a fortification strategy that retains bioavailability through typical household preparation and storage.

Apply for this statement
BB-FN-03
Functional Foods, Nutrition & Smart Proteins

Functional Foods, Nutrition & Smart Proteins

Gut microbiome-informed functional food

Design a food or supplement with a measurable microbiome-linked health outcome and a validation plan.

Apply for this statement
BB-FN-04
Functional Foods, Nutrition & Smart Proteins

Functional Foods, Nutrition & Smart Proteins

Clean-label preservation for packaged foods

Replace a synthetic preservative with a biological alternative without compromising safety or shelf life.

Apply for this statement
BB-FN-05
Functional Foods, Nutrition & Smart Proteins

Functional Foods, Nutrition & Smart Proteins

Nutrition intervention for school and anganwadi programmes

Propose a product and delivery model that measurably improves child nutrition within existing public programme constraints.

Apply for this statement
BB-EV-01
Environmental, Industrial & Waste-to-Value Biotech

Environmental, Industrial & Waste-to-Value Biotech

Bioremediation of industrial effluent

Treat a specific contaminant stream using microbial or enzymatic routes, with monitoring and disposal of the resulting biomass.

Apply for this statement
BB-EV-02
Environmental, Industrial & Waste-to-Value Biotech

Environmental, Industrial & Waste-to-Value Biotech

Plastic and textile waste depolymerisation

Convert a hard-to-recycle waste polymer into reusable monomers or value-added products using biological catalysts.

Apply for this statement
BB-EV-03
Environmental, Industrial & Waste-to-Value Biotech

Environmental, Industrial & Waste-to-Value Biotech

Agri-residue to high-value bioproducts

Turn crop residue that is currently burned into fuels, chemicals or materials with a workable collection model.

Apply for this statement
BB-EV-04
Environmental, Industrial & Waste-to-Value Biotech

Environmental, Industrial & Waste-to-Value Biotech

Industrial enzymes for greener processes

Engineer or source an enzyme that removes heat, solvent or water intensity from an existing industrial step.

Apply for this statement
BB-EV-05
Environmental, Industrial & Waste-to-Value Biotech

Environmental, Industrial & Waste-to-Value Biotech

Water quality biosensing for local bodies

Build a deployable biosensing approach that helps a municipality detect contamination events quickly and cheaply.

Apply for this statement
BB-OB-01
Open Bio Track

Open Bio Track

Biotech for accessibility and assistive care

Apply biological or biomedical engineering to improve independence for people with disabilities or chronic conditions.

Apply for this statement
BB-OB-02
Open Bio Track

Open Bio Track

Open-source lab hardware and reagents

Make an expensive lab capability affordable through open designs, local fabrication or reagent substitution.

Apply for this statement
BB-OB-03
Open Bio Track

Open Bio Track

Biotechnology education and skilling tools

Create a tool or curriculum that gives students genuine hands-on biotech experience without a well-funded lab.

Apply for this statement
BB-OB-04
Open Bio Track

Open Bio Track

Synthetic biology for a local unmet need

Use engineered biology responsibly to solve a problem specific to your region, including a biosafety discussion.

Apply for this statement
BB-OB-05
Open Bio Track

Open Bio Track

Bio-based materials for everyday products

Replace a petrochemical material in a common product with a bio-based alternative that performs comparably.

Apply for this statement
BB-OB-06
Open Bio Track

Open Bio Track

Wildcard — your own bio-related problem

Bring a bio-related problem of your own. You must supply a self-proposed title and justify the need, feasibility and impact.

Wildcard · Propose your ownApply for this statement